Product Name: 2-Methoxy-1-Propanol
Synonyms: Propylene glycol monomethyl ether, PGME
Chemical Formula: C4H10O2
CAS Number: 1589-47-5
Manufacturer: Contact local supplier or manufacturer for specific details
Recommended Use: Solvent in paints, inks, cleaners, and industrial applications
Emergency Contact: Refer to manufacturer's corporate emergency number or local poison control center
Restrictions on Use: Not intended for food, drug, or cosmetic purposes
GHS Classification: Eye irritation – Category 2A; Specific target organ toxicity – single exposure (narcotic effects) Category 3
Label Elements: Exclamation mark symbol; Signal Word: Warning
Hazard Statements: Causes serious eye irritation; May cause drowsiness or dizziness
Precautionary Statements: Avoid breathing vapors or mist; Wash exposed skin thoroughly after handling; Use only outdoors or in a well-ventilated area; Wear protective gloves and eye protection
Possible Routes of Exposure: Inhalation, Skin Contact, Eye Contact, Ingestion
Symptoms: Eye redness, watering, dizziness, headache, drowsiness, nausea
Environmental Hazards: Not classified as hazardous to the environment under standard GHS criteria, but spills can harm aquatic life
Chemical Name: 2-Methoxy-1-Propanol
Common Name: Propylene glycol monomethyl ether
CAS Number: 1589-47-5
Concentration: Typically 98% or higher (as supplied), minor water and trace impurities possible
Impurities/Other Additives: None expected above 1% threshold; check supplier details for quality or batch-specific composition
Inhalation: Move affected person to fresh air; keep at rest in a position comfortable for breathing; seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing; wash skin thoroughly with water and soap; seek care if irritation or redness continues
Eye Contact: Rinse cautiously with water for several minutes, removing contact lenses if easy; continue rinsing; consult an eye specialist if irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting; seek immediate medical advice
Most Important Symptoms: Irritation of eyes, respiratory tract depression, confusion, headache, drowsiness, nausea
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, water fog, carbon dioxide
Unsuitable Extinguishing Media: Direct water jets may spread burning substance
Hazards from Combustion: Produces carbon monoxide and carbon dioxide upon burning; toxic fumes possible
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective suit
Fire/Explosion Risk: Flammable liquid and vapor; vapors may travel along floor to ignition source and flash back; containers under heat may rupture\n
Special Procedures: Cool exposed containers with water spray; prevent run-off from entering sewers or waterways
Personal Precautions: Evacuate non-essential personnel; ventilate area; avoid inhalation of fumes; use suitable personal protective equipment including gloves, goggles, chemical-resistant clothing
Environmental Precautions: Prevent release into the environment, waterways, and drains; contain spill with inert materials such as sand
Methods and Materials for Containment: Absorb with non-combustible material and transfer to suitable container for disposal
Cleanup Procedures: Ventilate area; remove sources of ignition; dispose waste as per local and national regulations; wash area with soapy water after pick-up
Precautions for Safe Handling: Handle in well-ventilated area; keep away from heat, sparks, open flames, and hot surfaces; ground and bond containers during transfer; avoid skin and eye contact; do not inhale vapors
Advice on General Occupational Hygiene: Do not eat, drink, or smoke while using this material; wash hands and face after handling
Storage Conditions: Store in a cool, well-ventilated area away from direct sunlight, oxidizers, acids, and sources of ignition; keep container tightly closed and properly labeled
Incompatible Materials: Strong acids, oxidizers, strong bases; avoid storage in containers with copper, aluminum, or their alloys
Specific Storage Requirements: Use explosion-proof equipment; keep in containers made of compatible materials like fluorinated polymers or stainless steel
Occupational Exposure Limits: ACGIH TLV 50 ppm (Skin); OSHA PEL 100 ppm TWA
Engineering Controls: Use local exhaust ventilation or process enclosures to reduce exposure; provide adequate general ventilation
Eye Protection: Safety glasses or chemical goggles required
Skin Protection: Chemical-resistant gloves, long-sleeved clothing to minimize skin contact
Respiratory Protection: Use NIOSH-approved respirators for vapor concentrations above recommended limits; air-supplied respirators for high exposures
Environmental Exposure Controls: Use spill containment to avoid release; follow local environmental regulations
Appearance: Clear, colorless liquid
Odor: Sweet, ether-like
Odor Threshold: Not available
pH: Typically neutral as supplied
Melting Point/Freezing Point: -96°C
Boiling Point: 120–124°C
Flash Point: 31°C (closed cup)
Evaporation Rate: 0.38 (Butyl acetate = 1)
Flammability: Flammable liquid and vapor
Upper/Lower Flammability Limits: 1.5% – 13.1% (v/v in air)
Vapor Pressure: 10.4 mmHg at 25°C
Vapor Density: 2.6 (Air = 1)
Relative Density: 0.92 g/cm³ at 20°C
Solubility: Completely miscible with water
Partition Coefficient (n-octanol/water): Log Kow = -0.44
Auto-ignition Temperature: 287°C
Decomposition Temperature: Not determined
Viscosity: 2.3 mPa.s at 20°C
Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: May react violently with strong oxidizers
Conditions to Avoid: Heat, flame, sparks, static discharge, strong light
Incompatible Materials: Strong oxidizing agents, acids, alkali metals, peroxides
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, potentially irritating aldehydes in case of fire
Polymerization: Does not undergo hazardous polymerization under normal conditions
Routes of Exposure: Inhalation, skin absorption, eye and mucous membrane contact
Acute Toxicity: Oral LD50 (rat): 5660 mg/kg; Dermal LD50 (rabbit): 13500 mg/kg; Inhalation LC50: Not established
Skin Corrosion/Irritation: Mildly irritating on repeated/prolonged exposure
Eye Damage/Irritation: Causes moderate to severe eye irritation
Respiratory Sensitization: No evidence of sensitizing effect
Chronic Effects: Chronic repeated exposure at high levels may affect central nervous system (headache, dizziness, drowsiness); no information supporting carcinogenicity or mutagenicity in available literature
Other Effects: High vapor concentrations may cause narcosis; not recognized as reproductive toxin at typical workplace levels via major regulatory bodies
Toxicity to Aquatic Organisms: LC50 (fish, 96h): ~5,400 mg/L (Lepomis macrochirus); EC50 (Daphnia magna, 48h): >1,000 mg/L
Persistence and Degradability: Rapidly biodegradable in environment; >80% within 28 days in standard tests
Bioaccumulation Potential: Low, log Kow indicates unlikely to bioaccumulate
Mobility in Soil: Very mobile; will partition primarily to water, not expected to strongly adsorb to soil
Other Adverse Effects: High concentrations may affect aquatic microorganism activity; proper limits to releases recommended by local regulations
Degradation Products: Produces carbon oxides and small organics upon degradation
Waste Treatment Methods: Waste must be handled in accordance with local, regional, and national regulations; prefer incineration in authorized facilities; recycle or recover if feasible
Container Disposal: Containers should be properly emptied and recycled or disposed of via approved methods; avoid reuse of contaminated containers
Precautions: Prevent contamination of ground and waterways from spills; never discharge to sewer unless permitted by authorities
Hazard Classification: Considered hazardous waste under some jurisdictions; check RCRA or local equivalent
Special Requirements: Consult relevant local guidelines to ensure safe and legal handling and disposal
UN Number: UN 3092
Proper Shipping Name: 2-Methoxy-1-Propanol
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Marine Pollutant: Not regulated as marine pollutant
Environmental Hazards: Not classified as environmentally hazardous for transport purposes
Special Transport Precautions: Avoid sources of heat, direct sunlight, and ignition during transit; use spill-proof containers; ensure clear labeling
Other Information: Emergency response guides provided with shipping documents; check country-specific regulations for added requirements
OSHA: Regulated as hazardous under 29 CFR 1910.1200
TSCA: Listed on US Toxic Substances Control Act inventory
EU REACH: Registered; subject to certain safety measures in Europe
WHMIS Classification (Canada): B2 – Flammable Liquid; D2B – Toxic
SARA Title III: Typically not subject to Section 313; check inventory or supplier details
California Proposition 65: No known chemicals in this product listed as carcinogens or reproductive toxins
Other Standards: Subject to workplace safety and chemical reporting requirements in most industrialized countries; check local, state, and national regulations for additional restrictions or reporting obligations
