Material Safety Data Sheet: Dipropylene Glycol

Identification

Product Name: Dipropylene Glycol
Chemical Formula: C6H14O3
CAS Number: 25265-71-8
Synonyms: DPG, DPG (Typical), 2-(2-Hydroxypropoxy)-1-propanol
Product Use: Manufacturing cosmetics, fragrances, industrial solvents, plasticizers, de-icing fluids, hydraulic brake fluids
Manufacturer: Information provided on label or supplier’s documents
Emergency Phone: Number given by supplier (refer to shipment details)

Hazard Identification

GHS Classification: Not classified as hazardous under Globally Harmonized System
GHS Label Elements: No symbol or signal word required
Potential Health Effects: Mild irritation to eyes, low toxicity by inhalation or skin contact, can slightly irritate skin or respiratory tract with prolonged or repeated exposure
Routes of Exposure: Skin contact, eye contact, ingestion, inhalation of vapor or mist
Environmental Hazards: Expected to have low environmental impact but spills may harm aquatic life

Composition / Information on Ingredients

Substance: Dipropylene Glycol
Content: >99% by weight
Impurities: Trace amounts of tripropylene glycol and water may be found
EINECS Number: 246-770-3

First Aid Measures

Inhalation: Move person to fresh air if exposed to high vapor levels; seek medical attention if symptoms like cough or dizziness develop
Skin Contact: Remove contaminated clothing; wash well with soap and water; get advice if irritation continues
Eye Contact: Rinse cautiously with water for several minutes, removing contact lenses if present, and continue rinsing until discomfort eases
Ingestion: Rinse mouth, do not induce vomiting, and get medical help if any discomfort or symptoms develop
Most Important Symptoms and Effects: Eye and mild skin irritation, headache with high inhalation, unlikely to cause life-threatening effects

Fire-Fighting Measures

Flammability: Low fire hazard, not easily ignited under normal conditions
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry powder, carbon dioxide
Unsuitable Media: Direct stream of water may scatter liquid
Hazardous Combustion Products: Carbon monoxide, carbon dioxide released in a fire
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear to avoid inhaling gases or combustion products
Additional Info: Cool closed containers under fire exposure and contain runoff to prevent entry into the environment

Accidental Release Measures

Personal Precautions: Avoid breathing vapor or mist, ventilate area, wear protective clothing including gloves and eye protection
Environmental Precautions: Prevent further spillage or leakage, do not allow material to enter watercourses
Methods for Cleanup: Absorb with inert material (sand, earth, vermiculite), transfer to suitable container for disposal
Spill Response: Wash contaminated surface with water after initial cleanup, ensure proper ventilation

Handling and Storage

Handling: Wear appropriate personal protection to avoid eye and skin contact, use only in well-ventilated areas to minimize vapor build-up, wash hands after use and remove contaminated clothing
Storage: Store in closed, labeled containers in cool, dry, well-ventilated area away from incompatible substances like strong acids or oxidizers, keep away from heat and direct sunlight
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hygiene Measures: Do not eat, drink, or smoke while using this product, always wash thoroughly after handling

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific value assigned in most jurisdictions, general limit for nuisance dust or vapor may apply (check local regulations)
Engineering Controls: Use adequate ventilation or local exhaust to maintain exposure levels
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), splash-proof goggles, and, if exposure risk exists, long sleeves and pants
Respiratory Protection: Use an approved respirator if ventilation is not enough and vapor concentrations rise
Environmental Exposure: Use containment measures to avoid environmental release during use or waste disposal

Physical and Chemical Properties

Appearance: Clear, colorless, odorless, slightly viscous liquid
Odor: Faint, mild
Boiling Point: Approx. 230°C (446°F)
Melting Point: -80°C (-112°F)
Flash Point: 138°C (280°F)
Vapor Pressure: <0.01 mm Hg @ 20°C
Solubility: Miscible in water and most organic solvents
Specific Gravity: 1.023 @ 20°C
pH: Neutral (6-7) in solution
Viscosity: About 58 mPa.s @ 20°C

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and recommended storage conditions
Hazardous Polymerization: Not expected
Conditions to Avoid: Excessive heat, open flames, direct sunlight, freezing
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition: Breakdown may release carbon monoxide, carbon dioxide when heated strongly or burned

Toxicological Information

Acute Toxicity: Oral LD50 (rat) 14800–30000 mg/kg, low toxicity on skin and in eye contact
Skin Irritation: Not classified as an irritant, mild temporary irritation can occur
Eye Irritation: Mild irritation possible, not classified as damaging
Inhalation Risk: Low at ordinary temperatures and uses, vapor inhalation unlikely to cause harm
Chronic Effects: No reliable evidence of long-term hazards in typical occupational exposure
Sensitization: Not known to cause skin or respiratory sensitization
Carcinogenicity/Mutagenicity: No evidence of carcinogenic or mutagenic properties by current research

Ecological Information

Ecotoxicity: Not anticipated to cause significant toxicity to aquatic organisms or plants under normal conditions
Persistence and Degradability: Biodegradable in the environment, breaks down by natural processes
Bioaccumulation: Product does not accumulate significantly in aquatic species
Mobility in Soil: Product migrates in soil and dissolves in groundwater, but large spills should be avoided
Other Adverse Effects: Large releases may disrupt oxygen balance and cause ecosystem harm

Disposal Considerations

Waste Disposal: Collect and dispose of in accordance with local, regional, and national regulations
Container Disposal: Empty containers thoroughly before recycling or disposal, triple rinse if possible
Precautions: Do not discharge to sewers, waterways, or soil
Recommended Disposal Method: Incineration or landfill at approved facility, check for hazardous waste qualifiers in your area

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated as a dangerous good
Transport Hazard Class: Not classified
Packing Group: None
Hazard Label: No hazard required
Special Precautions: Ensure containers are secure and correctly labeled during transit
Reportable Quantity: Not required under US DOT or IMDG/ICAO
Transport in Bulk: Follow all applicable bulk transport requirements for safe handling and storage

Regulatory Information

Inventory Status: Listed on TSCA, REACH, EINECS, DSL, AICS, ENCS, and other major chemical inventories
US Regulations: Not considered hazardous under OSHA Hazard Communication Standard
EU Regulations: Not classified as dangerous under EC No. 1272/2008 (CLP/GHS)
Other Regulatory Listings: Product typically listed under appropriate sections for safe use in cosmetics and industrial processes
SARA Title III: Not listed as hazardous
Labeling Requirements: Handle per workplace requirements for hygiene and ventilation, use appropriate warnings on containers